CYP3A genetic variation and taxane-induced peripheral neuropathy: a systematic review, meta-analysis, and candidate gene study

Background: Taxane-induced peripheral neuropathy (TIPN) is an important cause of premature treatment cessation and dose-limitation in cancer therapy. It also reduces quality of life and survivorship in affected patients. Genetic polymorphisms in the CYP3A family have been investigated but the findin...

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Detalles Bibliográficos
Autores principales: McEvoy, Laurence, Cliff, Joanne, Carr, Daniel F, Jorgensen, Andrea, Lord, Rosemary, Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352989/
https://www.ncbi.nlm.nih.gov/pubmed/37469869
http://dx.doi.org/10.3389/fphar.2023.1178421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352989/
https://www.ncbi.nlm.nih.gov/pubmed/37469869
http://dx.doi.org/10.3389/fphar.2023.1178421

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