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PLGA/BGP/Nef porous composite restrains osteoclasts by inhibiting the NF-κB pathway, enhances IGF-1-mediated osteogenic differentiation and promotes bone regeneration

BACKGROUND: Novel bone substitutes are urgently needed in experimental research and clinical orthopaedic applications. There are many traditional Chinese medicines that have effects on bone repair. However, application of natural medicines in traditional Chinese medicine to bone tissue engineering a...

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Detalles Bibliográficos
Autores principales: Wu, Feng, Wu, Zhenxu, Ye, Zhijun, Niu, Guoqing, Ma, Zhiliang, Zhang, Peibiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353098/
https://www.ncbi.nlm.nih.gov/pubmed/37461106
http://dx.doi.org/10.1186/s13036-023-00354-8