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PLGA/BGP/Nef porous composite restrains osteoclasts by inhibiting the NF-κB pathway, enhances IGF-1-mediated osteogenic differentiation and promotes bone regeneration
BACKGROUND: Novel bone substitutes are urgently needed in experimental research and clinical orthopaedic applications. There are many traditional Chinese medicines that have effects on bone repair. However, application of natural medicines in traditional Chinese medicine to bone tissue engineering a...
Autores principales: | Wu, Feng, Wu, Zhenxu, Ye, Zhijun, Niu, Guoqing, Ma, Zhiliang, Zhang, Peibiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353098/ https://www.ncbi.nlm.nih.gov/pubmed/37461106 http://dx.doi.org/10.1186/s13036-023-00354-8 |
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