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How Cryo-EM Has Expanded Our Understanding of Membrane Transporters
Over the past two decades, technological advances in membrane protein structural biology have provided insight into the molecular mechanisms that transporters use to move diverse substrates across the membrane. However, the plasticity of these proteins’ ligand binding pockets, which allows them to b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353158/ https://www.ncbi.nlm.nih.gov/pubmed/37438132 http://dx.doi.org/10.1124/dmd.122.001004 |