How Cryo-EM Has Expanded Our Understanding of Membrane Transporters

Over the past two decades, technological advances in membrane protein structural biology have provided insight into the molecular mechanisms that transporters use to move diverse substrates across the membrane. However, the plasticity of these proteins’ ligand binding pockets, which allows them to b...

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Detalles Bibliográficos
Autores principales: Baril, Stefanie A., Gose, Tomoka, Schuetz, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2023
Materias:
50th Anniversary Celebration Collection Special Section on Perspective on Drug Metabolism and Disposition, Part II—Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353158/
https://www.ncbi.nlm.nih.gov/pubmed/37438132
http://dx.doi.org/10.1124/dmd.122.001004

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