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Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration in the MDA-MB-435S melanoma cell line

BACKGROUND: Focal adhesions (FAs) are integrin-containing, multi-protein structures that link intracellular actin to the extracellular matrix and trigger multiple signaling pathways that control cell proliferation, differentiation, survival and motility. Microtubules (MTs) are stabilized in the vici...

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Detalles Bibliográficos
Autores principales: Lončarić, Marija, Stojanović, Nikolina, Rac-Justament, Anja, Coopmans, Kaatje, Majhen, Dragomira, Humphries, Jonathan D., Humphries, Martin J., Ambriović-Ristov, Andreja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353188/
https://www.ncbi.nlm.nih.gov/pubmed/37460977
http://dx.doi.org/10.1186/s11658-023-00473-6