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Vaccination with a ZNF2(oe) Strain of Cryptococcus Provides Long-Lasting Protection against Cryptococcosis and Is Effective in Immunocompromised Hosts

Systemic cryptococcosis is fatal without treatment. Even with the current antifungal therapies, this disease kills 180,000 of 225,000 infected people annually. Exposure to the causative environmental fungus Cryptococcus neoformans is universal. Either reactivation of a latent infection or an acute i...

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Detalles Bibliográficos
Autores principales: Pham, Tuyetnhu, Li, Yeqi, Watford, Wendy, Lin, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353382/
https://www.ncbi.nlm.nih.gov/pubmed/37338404
http://dx.doi.org/10.1128/iai.00198-23