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No Association between the Plasmodium vivax crt-o MS334 or In9pvcrt Polymorphisms and Chloroquine Failure in a Pre-Elimination Clinical Cohort from Malaysia with a Large Clonal Expansion

Increasing reports of resistance to a frontline malaria blood-stage treatment, chloroquine (CQ), raises concerns for the elimination of Plasmodium vivax. The absence of an effective molecular marker of CQ resistance in P. vivax greatly constrains surveillance of this emerging threat. A recent geneti...

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Detalles Bibliográficos
Autores principales: Rumaseb, Angela, Moraes Barros, Roberto R., Sá, Juliana M., Juliano, Jonathan J., William, Timothy, Braima, Kamil A., Barber, Bridget E., Anstey, Nicholas M., Price, Ric N., Grigg, Matthew J., Marfurt, Jutta, Auburn, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353443/
https://www.ncbi.nlm.nih.gov/pubmed/37314336
http://dx.doi.org/10.1128/aac.01610-22