Cargando…

Facile synthesis of new N-(aminocycloalkylene)amino acid compounds using chiral triflate esters with N-Boc-aminopyrrolidines and N-Boc-aminopiperidines

In this study, we prepared a series of new N-(aminocycloalkylene)amino acid derivatives for use in chiral building blocks. The method was based on the conversion of enantiopure α-hydroxy acid esters into the corresponding chiral triflate esters, which were displaced by a nucleophilic substitution S(...

Descripción completa

Detalles Bibliográficos
Autores principales: Matulevičiūtė, Gita, Kleizienė, Neringa, Račkauskienė, Greta, Martynaitis, Vytas, Bieliauskas, Aurimas, Šachlevičiūtė, Urtė, Jankauskas, Rokas, Bartkus, Martynas R., Sløk, Frank A., Šačkus, Algirdas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353522/
https://www.ncbi.nlm.nih.gov/pubmed/37469966
http://dx.doi.org/10.1039/d3ra03060a