Generation of two induced pluripotent stem cell lines with heterozygous and homozygous amyotrophic lateral sclerosis-causing mutation R521G (c.1561C > G) in FUS gene

Mutations in the RNA-binding protein FUS (fused in sarcoma) are linked to amyotrophic lateral sclerosis (ALS), but the pathogenesis is not fully understood. For modeling ALS, here we generated two induced pluripotent stem cell (iPSC) lines carrying the heterozygous and homozygous R521G (c.1561C >...

Descripción completa

Detalles Bibliográficos
Autores principales: Akter, Masuma, Cui, Haochen, Hosain, Abir, Ding, Baojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353567/
https://www.ncbi.nlm.nih.gov/pubmed/36965406
http://dx.doi.org/10.1016/j.scr.2023.103078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353567/
https://www.ncbi.nlm.nih.gov/pubmed/36965406
http://dx.doi.org/10.1016/j.scr.2023.103078

Ejemplares similares