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Phylogenetic and Genomic Characterization of Whole Genome Sequences of Ocular Herpes Simplex Virus Type 1 Isolates Identifies Possible Virulence Determinants in Humans

PURPOSE: There are limited data on the prevalence and genetic diversity of herpes simplex virus type 1 (HSV-1) virulence genes in ocular isolates. Here, we sequenced 36 HSV-1 ocular isolates, collected by the Bascom Palmer Eye Institute, a university-based eye hospital, from three different ocular a...

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Detalles Bibliográficos
Autores principales: Chau, Viet Q., Kolb, Aaron W., Miller, Darlene L., Yannuzzi, Nicolas A., Brandt, Curtis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353747/
https://www.ncbi.nlm.nih.gov/pubmed/37450309
http://dx.doi.org/10.1167/iovs.64.10.16