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Pro-fibrogenic and adipogenic aspects of chronic muscle degeneration are contributed by distinct stromal cell subpopulations

Chronic skeletal muscle degeneration is characterized by fiber atrophy accompanied by deposition of extracellular matrix (ECM) components and fatty infiltration. Excessive accumulation of ECM leads to fibrosis via the contribution of fibro-adipogenic precursors (FAPs). Fibrosis also accompanies disu...

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Detalles Bibliográficos
Autores principales: Özdemir, Cansu, Akçay, Duygu, Yöyen-Ermiş, Diğdem, Taşkıran, Ekim Zihni, Soylu-Kucharz, Rana, Esendağlı, Güneş, Kocaefe, Yusuf Çetin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353787/
https://www.ncbi.nlm.nih.gov/pubmed/37463149
http://dx.doi.org/10.1371/journal.pone.0288800