Cleavage of the V-ATPase associated prorenin receptor is mediated by PACE4 and is essential for growth of prostate cancer cells

Phosphatase and tensin homolog (PTEN) mutation is common in prostate cancer during progression to metastatic and castration resistant forms. We previously reported that loss of PTEN function in prostate cancer leads to increased expression and secretion of the Prorenin Receptor (PRR) and its soluble...

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Detalles Bibliográficos
Autores principales: Mohammad, Amro H., Couture, Frédéric, Gamache, Isabelle, Chen, Owen, El-Assaad, Wissal, Abdel-Malak, Nelly, Kwiatkowska, Anna, Muller, William, Day, Robert, Teodoro, Jose G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353799/
https://www.ncbi.nlm.nih.gov/pubmed/37463144
http://dx.doi.org/10.1371/journal.pone.0288622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353799/
https://www.ncbi.nlm.nih.gov/pubmed/37463144
http://dx.doi.org/10.1371/journal.pone.0288622

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