Small change, big difference: A promising praziquantel derivative designated P96 with broad-spectrum antischistosomal activity for chemotherapy of schistosomiasis japonica

BACKGROUND: Praziquantel (PZQ) has been the first line antischistosomal drug for all species of Schistosoma, and the only available drug for schistosomiasis japonica, without any alternative drugs since the 1980s. However, PZQ cannot prevent reinfection, and cannot cure schistosomiasis thoroughly be...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Dong, Lan-Lan, Sun, Huan, Huang, Ping, Zhang, Run-Ze, Wang, Xin-Yi, Sun, De-Qun, Xia, Chao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353801/
https://www.ncbi.nlm.nih.gov/pubmed/37410790
http://dx.doi.org/10.1371/journal.pntd.0011215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353801/
https://www.ncbi.nlm.nih.gov/pubmed/37410790
http://dx.doi.org/10.1371/journal.pntd.0011215

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