Fibrinolytic and antibiotic treatment of prosthetic vascular graft infections in a novel rat model

OBJECTIVES: We developed a rat model of prosthetic vascular graft infection to assess, whether the fibrinolytic tissue plasminogen activator (tPA) could increase the efficacy of antibiotic therapy. MATERIALS AND METHODS: Rats were implanted a polyethylene graft in the common carotid artery, pre-inoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Johansen, Mikkel Illemann, Rahbek, Søren Jensen, Jensen-Fangel, Søren, Minero, Gabriel Antonio S., Jensen, Louise Kruse, Larsen, Ole Halfdan, Erikstrup, Lise Tornvig, Seefeldt, Anders Marthinsen, Østergaard, Lars, Meyer, Rikke Louise, Jørgensen, Nis Pedersen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353806/
https://www.ncbi.nlm.nih.gov/pubmed/37463137
http://dx.doi.org/10.1371/journal.pone.0287671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353806/
https://www.ncbi.nlm.nih.gov/pubmed/37463137
http://dx.doi.org/10.1371/journal.pone.0287671

Ejemplares similares