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Fibrinolytic and antibiotic treatment of prosthetic vascular graft infections in a novel rat model
OBJECTIVES: We developed a rat model of prosthetic vascular graft infection to assess, whether the fibrinolytic tissue plasminogen activator (tPA) could increase the efficacy of antibiotic therapy. MATERIALS AND METHODS: Rats were implanted a polyethylene graft in the common carotid artery, pre-inoc...
Autores principales: | Johansen, Mikkel Illemann, Rahbek, Søren Jensen, Jensen-Fangel, Søren, Minero, Gabriel Antonio S., Jensen, Louise Kruse, Larsen, Ole Halfdan, Erikstrup, Lise Tornvig, Seefeldt, Anders Marthinsen, Østergaard, Lars, Meyer, Rikke Louise, Jørgensen, Nis Pedersen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353806/ https://www.ncbi.nlm.nih.gov/pubmed/37463137 http://dx.doi.org/10.1371/journal.pone.0287671 |
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