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USP12 promotes antiviral responses by deubiquitinating and stabilizing IFI16

Deubiquitinating enzymes (DUBs) regulate antiviral immune response through targeting DNA sensor signaling pathway members. As one of the DNA sensors, interferon (IFN)-γ inducible protein 16 (IFI16) play a major role in response to virus infections through activating the canonical STING/TBK-1/IRF3 si...

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Detalles Bibliográficos
Autores principales: Fu, Yuling, Zhan, Xiaoxia, You, Xiaolong, Nie, Dingnai, Mai, Haiyan, Chen, Yitian, He, Shitong, Sheng, Junli, Zeng, Zhijie, Li, Hongwei, Li, Jinlong, Hu, Shengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353808/
https://www.ncbi.nlm.nih.gov/pubmed/37410794
http://dx.doi.org/10.1371/journal.ppat.1011480