Differential fibril morphologies and thermostability determine functional roles of Staphylococcus aureus PSMα1 and PSMα3

Phenol-soluble modulins (PSMs) are virulent peptides secreted by staphylococci that undergo self-assembly into amyloid fibrils. This study focuses on Staphylococcus aureus PSMα1 and PSMα3, which share homologous sequences but exhibit distinct amyloid fibril structures. Upon subjecting PSMα1 to an 80...

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Detalles Bibliográficos
Autores principales: Rayan, Bader, Barnea, Eilon, Khokhlov, Alexander, Upcher, Alexander, Landau, Meytal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353841/
https://www.ncbi.nlm.nih.gov/pubmed/37469708
http://dx.doi.org/10.3389/fmolb.2023.1184785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353841/
https://www.ncbi.nlm.nih.gov/pubmed/37469708
http://dx.doi.org/10.3389/fmolb.2023.1184785

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