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A Reliable and Effective UPLC-MS/MS Method for the Determination of Oprozomib in Rat Plasma
Oprozomib, as a second-generation orally bioavailable protease inhibitor (PI), is undergoing clinical evaluation for the treatment of haematological malignancies. In relapsed refractory multiple myeloma (RRMM) patients, oprozomib has shown good efficacy as a single agent or combination therapy. In t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353894/ https://www.ncbi.nlm.nih.gov/pubmed/37469971 http://dx.doi.org/10.1155/2023/3678599 |