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A Reliable and Effective UPLC-MS/MS Method for the Determination of Oprozomib in Rat Plasma

Oprozomib, as a second-generation orally bioavailable protease inhibitor (PI), is undergoing clinical evaluation for the treatment of haematological malignancies. In relapsed refractory multiple myeloma (RRMM) patients, oprozomib has shown good efficacy as a single agent or combination therapy. In t...

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Detalles Bibliográficos
Autores principales: Li, Xia, Liu, Ya-nan, Zhang, En, Xu, Ren-ai, Yang, Tingyong, Luo, Shunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353894/
https://www.ncbi.nlm.nih.gov/pubmed/37469971
http://dx.doi.org/10.1155/2023/3678599