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Therapeutic utility of engineered myeloid cells in the tumor microenvironment

Despite promising results shown in hematologic tumors, immunotherapies for the treatment of solid tumors have mostly failed so far. The immunosuppressive tumor microenvironment and phenotype of tumor infiltrating macrophages are among the more prevalent reasons for this failure. Tumor associated mac...

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Detalles Bibliográficos
Autores principales: Canella, Alessandro, Rajappa, Prajwal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353932/
https://www.ncbi.nlm.nih.gov/pubmed/36854896
http://dx.doi.org/10.1038/s41417-023-00600-7