A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease

Identification of individuals at highest risk of coronary artery disease (CAD)—ideally before onset—remains an important public health need. Prior studies have developed genome-wide polygenic scores to enable risk stratification, reflecting the substantial inherited component to CAD risk. Here we de...

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Detalles Bibliográficos
Autores principales: Patel, Aniruddh P., Wang, Minxian, Ruan, Yunfeng, Koyama, Satoshi, Clarke, Shoa L., Yang, Xiong, Tcheandjieu, Catherine, Agrawal, Saaket, Fahed, Akl C., Ellinor, Patrick T., Tsao, Philip S., Sun, Yan V., Cho, Kelly, Wilson, Peter W. F., Assimes, Themistocles L., van Heel, David A., Butterworth, Adam S., Aragam, Krishna G., Natarajan, Pradeep, Khera, Amit V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353935/
https://www.ncbi.nlm.nih.gov/pubmed/37414900
http://dx.doi.org/10.1038/s41591-023-02429-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353935/
https://www.ncbi.nlm.nih.gov/pubmed/37414900
http://dx.doi.org/10.1038/s41591-023-02429-x

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