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E2F1-mediated KDM4A-AS1 up-regulation promotes EMT of hepatocellular carcinoma cells by recruiting ILF3 to stabilize AURKA mRNA

Hepatocellular carcinoma (HCC) is a gastrointestinal tumor with high clinical incidence. Long non-coding RNAs (lncRNAs) play vital roles in modulating the growth and epithelial-mesenchymal transition (EMT) of HCC. However, the underlying mechanism of lncRNA KDM4A antisense RNA 1 (KDM4A-AS1) in HCC r...

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Detalles Bibliográficos
Autores principales: Shen, Hao-Ming, Zhang, Di, Xiao, Ping, Qu, Bin, Sun, Yi-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353940/
https://www.ncbi.nlm.nih.gov/pubmed/36973424
http://dx.doi.org/10.1038/s41417-023-00607-0