Cargando…

Human microglia show unique transcriptional changes in Alzheimer’s disease

Microglia, the innate immune cells of the brain, influence Alzheimer’s disease (AD) progression and are potential therapeutic targets. However, microglia exhibit diverse functions, the regulation of which is not fully understood, complicating therapeutics development. To better define the transcript...

Descripción completa

Detalles Bibliográficos
Autores principales: Prater, Katherine E., Green, Kevin J., Mamde, Sainath, Sun, Wei, Cochoit, Alexandra, Smith, Carole L., Chiou, Kenneth L., Heath, Laura, Rose, Shannon E., Wiley, Jesse, Keene, C. Dirk, Kwon, Ronald Y., Snyder-Mackler, Noah, Blue, Elizabeth E., Logsdon, Benjamin, Young, Jessica E., Shojaie, Ali, Garden, Gwenn A., Jayadev, Suman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353942/
https://www.ncbi.nlm.nih.gov/pubmed/37248328
http://dx.doi.org/10.1038/s43587-023-00424-y