Chromatin accessibility dynamics of neurogenic niche cells reveal defects in neural stem cell adhesion and migration during aging

The regenerative potential of brain stem cell niches deteriorates during aging. Yet the mechanisms underlying this decline are largely unknown. Here we characterize genome-wide chromatin accessibility of neurogenic niche cells in vivo during aging. Interestingly, chromatin accessibility at adhesion...

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Detalles Bibliográficos
Autores principales: Yeo, Robin W., Zhou, Olivia Y., Zhong, Brian L., Sun, Eric D., Navarro Negredo, Paloma, Nair, Surag, Sharmin, Mahfuza, Ruetz, Tyson J., Wilson, Mikaela, Kundaje, Anshul, Dunn, Alexander R., Brunet, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353944/
https://www.ncbi.nlm.nih.gov/pubmed/37443352
http://dx.doi.org/10.1038/s43587-023-00449-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353944/
https://www.ncbi.nlm.nih.gov/pubmed/37443352
http://dx.doi.org/10.1038/s43587-023-00449-3

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