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Development of a fast and precise potency test for BCG vaccine viability using flow cytometry compared to MTT and colony-forming unit assays

In a precarious world of rapidly growing pandemics, the field of vaccine production has witnessed considerable growth. Bacillus Calmette-Guérin (BCG) is a live-attenuated vaccine and a part of the immunization program in 157 countries. The quality control is based on a potency test through viable ce...

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Detalles Bibliográficos
Autores principales: Moghawry, Hend M., Rashed, Mohamed E., Gomaa, Kareeman, AbdelGhani, Sameh, Dishisha, Tarek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354009/
https://www.ncbi.nlm.nih.gov/pubmed/37464014
http://dx.doi.org/10.1038/s41598-023-38657-x