An optimized Nurr1 agonist provides disease-modifying effects in Parkinson’s disease models

The nuclear receptor, Nurr1, is critical for both the development and maintenance of midbrain dopamine neurons, representing a promising molecular target for Parkinson’s disease (PD). We previously identified three Nurr1 agonists (amodiaquine, chloroquine and glafenine) that share an identical chemi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Woori, Tripathi, Mohit, Kim, Chunhyung, Vardhineni, Satyapavan, Cha, Young, Kandi, Shamseer Kulangara, Feitosa, Melissa, Kholiya, Rohit, Sah, Eric, Thakur, Anuj, Kim, Yehan, Ko, Sanghyeok, Bhatia, Kaiya, Manohar, Sunny, Kong, Young-Bin, Sindhu, Gagandeep, Kim, Yoon-Seong, Cohen, Bruce, Rawat, Diwan S., Kim, Kwang-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354055/
https://www.ncbi.nlm.nih.gov/pubmed/37463889
http://dx.doi.org/10.1038/s41467-023-39970-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354055/
https://www.ncbi.nlm.nih.gov/pubmed/37463889
http://dx.doi.org/10.1038/s41467-023-39970-9

Ejemplares similares