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An optimized Nurr1 agonist provides disease-modifying effects in Parkinson’s disease models

The nuclear receptor, Nurr1, is critical for both the development and maintenance of midbrain dopamine neurons, representing a promising molecular target for Parkinson’s disease (PD). We previously identified three Nurr1 agonists (amodiaquine, chloroquine and glafenine) that share an identical chemi...

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Detalles Bibliográficos
Autores principales:	Kim, Woori, Tripathi, Mohit, Kim, Chunhyung, Vardhineni, Satyapavan, Cha, Young, Kandi, Shamseer Kulangara, Feitosa, Melissa, Kholiya, Rohit, Sah, Eric, Thakur, Anuj, Kim, Yehan, Ko, Sanghyeok, Bhatia, Kaiya, Manohar, Sunny, Kong, Young-Bin, Sindhu, Gagandeep, Kim, Yoon-Seong, Cohen, Bruce, Rawat, Diwan S., Kim, Kwang-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354055/ https://www.ncbi.nlm.nih.gov/pubmed/37463889 http://dx.doi.org/10.1038/s41467-023-39970-9

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