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Human blood neutrophils generate ROS through FcγR-signaling to mediate protection against febrile P. falciparum malaria

Blood phagocytes, such as neutrophils and monocytes, generate reactive oxygen species (ROS) as a part of host defense response against infections. We investigated the mechanism of Fcγ-Receptor (FcγR) mediated ROS production in these cells to understand how they contribute to anti-malarial immunity....

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Detalles Bibliográficos
Autores principales: Ofori, Ebenezer Addo, Garcia-Senosiain, Asier, Naghizadeh, Mohammad, Kana, Ikhlaq Hussain, Dziegiel, Morten Hanefeld, Adu, Bright, Singh, Subhash, Theisen, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354059/
https://www.ncbi.nlm.nih.gov/pubmed/37463969
http://dx.doi.org/10.1038/s42003-023-05118-0