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Cancer-associated fibroblast classification in single-cell and spatial proteomics data

Cancer-associated fibroblasts (CAFs) are a diverse cell population within the tumour microenvironment, where they have critical effects on tumour evolution and patient prognosis. To define CAF phenotypes, we analyse a single-cell RNA sequencing (scRNA-seq) dataset of over 16,000 stromal cells from t...

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Detalles Bibliográficos
Autores principales: Cords, Lena, Tietscher, Sandra, Anzeneder, Tobias, Langwieder, Claus, Rees, Martin, de Souza, Natalie, Bodenmiller, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354071/
https://www.ncbi.nlm.nih.gov/pubmed/37463917
http://dx.doi.org/10.1038/s41467-023-39762-1