Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3

Although Poly(ADP-ribose)-polymerases (PARPs) are key regulators of genome stability, how site-specific ADP-ribosylation regulates DNA repair is unclear. Here, we describe a novel role for PARP1 and PARP2 in regulating Rad52-dependent replication fork repair to maintain cell viability when homologou...

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Detalles Bibliográficos
Autores principales: Richards, Frederick, Llorca-Cardenosa, Marta J., Langton, Jamie, Buch-Larsen, Sara C., Shamkhi, Noor F., Sharma, Abhishek Bharadwaj, Nielsen, Michael L., Lakin, Nicholas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354178/
https://www.ncbi.nlm.nih.gov/pubmed/37463936
http://dx.doi.org/10.1038/s41467-023-40071-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354178/
https://www.ncbi.nlm.nih.gov/pubmed/37463936
http://dx.doi.org/10.1038/s41467-023-40071-w

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