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Calretinin-expressing islet cells are a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord
Unmyelinated non-peptidergic nociceptors (NP afferents) arborise in lamina II of the spinal cord and receive GABAergic axoaxonic synapses, which mediate presynaptic inhibition. However, until now the source of this axoaxonic synaptic input was not known. Here we provide evidence that it originates f...
Autores principales: | Davis, Olivia C., Dickie, Allen C., Mustapa, Marami B., Boyle, Kieran A., Browne, Tyler J., Gradwell, Mark A., Smith, Kelly M., Polgár, Erika, Bell, Andrew M., Kókai, Éva, Watanabe, Masahiko, Wildner, Hendrik, Zeilhofer, Hanns Ulrich, Ginty, David D., Callister, Robert J., Graham, Brett A., Todd, Andrew J., Hughes, David I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354228/ https://www.ncbi.nlm.nih.gov/pubmed/37464016 http://dx.doi.org/10.1038/s41598-023-38605-9 |
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