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RUFY3 regulates endolysosomes perinuclear positioning, antigen presentation and migration in activated phagocytes

Endo-lysosomes transport along microtubules and clustering in the perinuclear area are two necessary steps for microbes to activate specialized phagocyte functions. We report that RUN and FYVE domain-containing protein 3 (RUFY3) exists as two alternative isoforms distinguishable by the presence of a...

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Detalles Bibliográficos
Autores principales: Char, Rémy, Liu, Zhuangzhuang, Jacqueline, Cédric, Davieau, Marion, Delgado, Maria-Graciela, Soufflet, Clara, Fallet, Mathieu, Chasson, Lionel, Chapuy, Raphael, Camosseto, Voahirana, Strock, Eva, Rua, Rejane, Almeida, Catarina R., Su, Bing, Lennon-Duménil, Ana-Maria, Nal, Beatrice, Roquilly, Antoine, Liang, Yinming, Méresse, Stéphane, Gatti, Evelina, Pierre, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354229/
https://www.ncbi.nlm.nih.gov/pubmed/37463962
http://dx.doi.org/10.1038/s41467-023-40062-x