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RUFY3 regulates endolysosomes perinuclear positioning, antigen presentation and migration in activated phagocytes
Endo-lysosomes transport along microtubules and clustering in the perinuclear area are two necessary steps for microbes to activate specialized phagocyte functions. We report that RUN and FYVE domain-containing protein 3 (RUFY3) exists as two alternative isoforms distinguishable by the presence of a...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354229/ https://www.ncbi.nlm.nih.gov/pubmed/37463962 http://dx.doi.org/10.1038/s41467-023-40062-x |