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Differences in metabolic transport and resistance mechanisms of Abemaciclib, Palbociclib, and Ribociclib

Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) play a crucial role in cancer treatment, particularly in breast cancer, and their mechanism of drug resistance is a topic of global interest in research. Hence, it is vital to comprehend the distinctions between various CDK4/6i, including their mechan...

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Detalles Bibliográficos
Autores principales: Zhu, Zhimin, Zhu, Qiongni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354263/
https://www.ncbi.nlm.nih.gov/pubmed/37475713
http://dx.doi.org/10.3389/fphar.2023.1212986