Novel kinetoplastid-specific cAMP binding proteins identified by RNAi screening for cAMP resistance in Trypanosoma brucei

Cyclic AMP signalling in trypanosomes differs from most eukaryotes due to absence of known cAMP effectors and cAMP independence of PKA. We have previously identified four genes from a genome-wide RNAi screen for resistance to the cAMP phosphodiesterase (PDE) inhibitor NPD-001. The genes were named c...

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Detalles Bibliográficos
Autores principales: Bachmaier, Sabine, Gould, Matthew K., Polatoglou, Eleni, Omelianczyk, Radoslaw, Brennand, Ana E., Aloraini, Maha A., Munday, Jane C., Horn, David, Boshart, Michael, de Koning, Harry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354285/
https://www.ncbi.nlm.nih.gov/pubmed/37475965
http://dx.doi.org/10.3389/fcimb.2023.1204707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354285/
https://www.ncbi.nlm.nih.gov/pubmed/37475965
http://dx.doi.org/10.3389/fcimb.2023.1204707

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