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Fibrosis—the tale of H3K27 histone methyltransferases and demethylases

Fibrosis, or excessive scarring, is characterized by the emergence of alpha-smooth muscle actin (αSMA)-expressing myofibroblasts and the excessive accumulation of fibrotic extracellular matrix (ECM). Currently, there is a lack of effective treatment options for fibrosis, highlighting an unmet need t...

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Detalles Bibliográficos
Autores principales: Basta, Morgan D., Petruk, Svetlana, Mazo, Alexander, Walker, Janice L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354294/
https://www.ncbi.nlm.nih.gov/pubmed/37476157
http://dx.doi.org/10.3389/fcell.2023.1193344