Cargando…

Fibrosis—the tale of H3K27 histone methyltransferases and demethylases

Fibrosis, or excessive scarring, is characterized by the emergence of alpha-smooth muscle actin (αSMA)-expressing myofibroblasts and the excessive accumulation of fibrotic extracellular matrix (ECM). Currently, there is a lack of effective treatment options for fibrosis, highlighting an unmet need t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Basta, Morgan D., Petruk, Svetlana, Mazo, Alexander, Walker, Janice L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354294/ https://www.ncbi.nlm.nih.gov/pubmed/37476157 http://dx.doi.org/10.3389/fcell.2023.1193344

Ejemplares similares

The Histone H3K27me3 Demethylases KDM6A/B Resist Anoikis and Transcriptionally Regulate Stemness-Related Genes
por: Shait Mohammed, Mohammed Razeeth, et al.
Publicado: (2022)

Targets of histone H3 lysine 9 methyltransferases
por: Levinsky, Aidan J., et al.
Publicado: (2022)

Epigenetic Control of Muscle Stem Cells: Focus on Histone Lysine Demethylases
por: Cicciarello, Delia, et al.
Publicado: (2022)

The Diverse Roles of Histone Demethylase KDM4B in Normal and Cancer Development and Progression
por: Wang, Zhongze, et al.
Publicado: (2022)

Histone Demethylase JMJD3 Mediated Doxorubicin-Induced Cardiomyopathy by Suppressing SESN2 Expression
por: Wang, Panxia, et al.
Publicado: (2020)

Histone Demethylase PHF8 Is Required for the Development of the Zebrafish Inner Ear and Posterior Lateral Line
por: He, Jing, et al.
Publicado: (2020)

Genome-Wide Histone H3K27 Acetylation Profiling Identified Genes Correlated With Prognosis in Papillary Thyroid Carcinoma
por: Zhang, Luyao, et al.
Publicado: (2021)

Structural Paradigms in the Recognition of the Nucleosome Core Particle by Histone Lysine Methyltransferases
por: Janna, Ashley, et al.
Publicado: (2020)

Emerin interacts with histone methyltransferases to regulate repressive chromatin at the nuclear periphery
por: Marano, Nicholas, et al.
Publicado: (2022)

Histone 3 Methyltransferases Alter Melanoma Initiation and Progression Through Discrete Mechanisms
por: DiNapoli, Sara E., et al.
Publicado: (2022)

Histone methyltransferase KMT2D contributes to the protection of myocardial ischemic injury
por: Liu, Shu-Bao, et al.
Publicado: (2022)

The Jumonji Domain-Containing Histone Demethylase Homolog 1D/lysine Demethylase 7A (JHDM1D/KDM7A) Is an Epigenetic Activator of RHOJ Transcription in Breast Cancer Cells
por: Zhang, Ziyu, et al.
Publicado: (2021)

Histone Lysine Demethylases KDM5B and KDM5C Modulate Genome Activation and Stability in Porcine Embryos
por: Glanzner, Werner Giehl, et al.
Publicado: (2020)

Corrigendum: The Jumonji Domain-Containing Histone Demethylase Homolog 1D/lysine Demethylase 7A (JHDM1D/KDM7A) Is an Epigenetic Activator of RHOJ Transcription in Breast Cancer Cells
por: Zhang, Ziyu, et al.
Publicado: (2021)

Epigenetic Deregulation of the Histone Methyltransferase KMT5B Contributes to Malignant Transformation in Glioblastoma
por: López, Virginia, et al.
Publicado: (2021)

Additional sex combs interacts with enhancer of zeste and trithorax and modulates levels of trimethylation on histone H3K4 and H3K27 during transcription of hsp70
por: Li, Taosui, et al.
Publicado: (2017)

Histone H3K27 methyltransferase EZH2 and demethylase JMJD3 regulate hepatic stellate cells activation and liver fibrosis
por: Jiang, Yan, et al.
Publicado: (2021)

Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts
por: Chen, Fengling, et al.
Publicado: (2021)

Histone lysine methyltransferase-related neurodevelopmental disorders: current knowledge and saRNA future therapies
por: Roth, Charlotte, et al.
Publicado: (2023)

Histone Arginine Methyltransferase CARM1-Mediated H3R26me2 Is Essential for Morula-to-Blastocyst Transition in Pigs
por: Cao, Zubing, et al.
Publicado: (2021)

Collateral Victim or Rescue Worker?—The Role of Histone Methyltransferases in DNA Damage Repair and Their Targeting for Therapeutic Opportunities in Cancer
por: He, Lishu, et al.
Publicado: (2021)

Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation
por: Kerenyi, Marc A, et al.
Publicado: (2013)

EZH2/EHMT2 Histone Methyltransferases Inhibit the Transcription of DLX5 and Promote the Transformation of Myelodysplastic Syndrome to Acute Myeloid Leukemia
por: Zheng, Zhuanzhen, et al.
Publicado: (2021)

H3K9 Methyltransferases Suv39h1 and Suv39h2 Control the Differentiation of Neural Progenitor Cells in the Adult Hippocampus
por: Guerra, Miguel V., et al.
Publicado: (2022)

Genome-Wide Analysis of H3K27me3 in Porcine Embryonic Muscle Development
por: Tan, Baohua, et al.
Publicado: (2021)

The histone H3K9 demethylase KDM3A promotes anoikis by transcriptionally activating pro-apoptotic genes BNIP3 and BNIP3L
por: Pedanou, Victoria E, et al.
Publicado: (2016)

Histone Deacetylase 11 Contributes to Renal Fibrosis by Repressing KLF15 Transcription
por: Mao, Lei, et al.
Publicado: (2020)

Histone Methyltransferase SETD1A Induces Epithelial-Mesenchymal Transition to Promote Invasion and Metastasis Through Epigenetic Reprogramming of Snail in Gastric Cancer
por: Wu, Jugang, et al.
Publicado: (2021)

m6A demethylase FTO and osteoporosis: potential therapeutic interventions
por: Huang, Mei, et al.
Publicado: (2023)

Dual inhibition of EZH2 and G9A/GLP histone methyltransferases by HKMTI-1-005 promotes differentiation of acute myeloid leukemia cells
por: Sbirkov, Y., et al.
Publicado: (2023)

Changes in nascent chromatin structure regulate activation of the pro-fibrotic transcriptome and myofibroblast emergence in organ fibrosis
por: Basta, Morgan D., et al.
Publicado: (2023)

Depletion of Demethylase KDM6 Enhances Early Neuroectoderm Commitment of Human PSCs
por: Meng, Yajing, et al.
Publicado: (2021)

MIR143 Inhibits Steroidogenesis and Induces Apoptosis Repressed by H3K27me3 in Granulosa Cells
por: Zhong, Yuyi, et al.
Publicado: (2020)

Interplay Between BALL and CREB Binding Protein Maintains H3K27 Acetylation on Active Genes in Drosophila
por: Shaukat, Ammad, et al.
Publicado: (2021)

Metabolism and Transcription in Cancer: Merging Two Classic Tales
por: Martín-Martín, Natalia, et al.
Publicado: (2018)

A Tale of Two States: Pluripotency Regulation of Telomeres
por: Novo, Clara Lopes
Publicado: (2021)

The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6
por: Qing, Yun, et al.
Publicado: (2014)

Lysine Methyltransferase Inhibitors Impair H4K20me2 and 53BP1 Foci in Response to DNA Damage in Sarcomas, a Synthetic Lethality Strategy
por: Campillo-Marcos, Ignacio, et al.
Publicado: (2021)

Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism
por: Cribbs, Adam P., et al.
Publicado: (2020)

Inactivation of the Euchromatic Histone-Lysine N-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks
por: Urrutia, Guillermo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ichasa069ipi04d1gan53skbk1