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MFN2 suppresses clear cell renal cell carcinoma progression by modulating mitochondria‐dependent dephosphorylation of EGFR

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is the most lethal renal cancer. An overwhelming increase of patients experience tumor progression and unfavorable prognosis. However, the molecular events underlying ccRCC tumorigenesis and metastasis remain unclear. Therefore, uncovering the unde...

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Detalles Bibliográficos
Autores principales: Luo, Li, Wei, Denghui, Pan, Yihui, Wang, Qiu‐Xia, Feng, Jian‐Xiong, Yu, Bing, Kang, Tiebang, Luo, Junhang, Yang, Jiefeng, Gao, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354417/
https://www.ncbi.nlm.nih.gov/pubmed/37378422
http://dx.doi.org/10.1002/cac2.12428