RIG-I agonist SLR10 promotes macrophage M1 polarization during influenza virus infection

RATIONALE: A family of short synthetic, triphosphorylated stem-loop RNAs (SLRs) have been designed to activate the retinoic-acid-inducible gene I (RIG-I) pathway and induce a potent interferon (IFN) response, which may have therapeutic potential. We investigated immune response modulation by SLR10....

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Detalles Bibliográficos
Autores principales: Wu, Wenxin, Zhang, Wei, Alexandar, Jeremy S., Booth, J. Leland, Miller, Craig A., Xu, Chao, Metcalf, Jordan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354434/
https://www.ncbi.nlm.nih.gov/pubmed/37475869
http://dx.doi.org/10.3389/fimmu.2023.1177624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354434/
https://www.ncbi.nlm.nih.gov/pubmed/37475869
http://dx.doi.org/10.3389/fimmu.2023.1177624

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