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RIG-I agonist SLR10 promotes macrophage M1 polarization during influenza virus infection
RATIONALE: A family of short synthetic, triphosphorylated stem-loop RNAs (SLRs) have been designed to activate the retinoic-acid-inducible gene I (RIG-I) pathway and induce a potent interferon (IFN) response, which may have therapeutic potential. We investigated immune response modulation by SLR10....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354434/ https://www.ncbi.nlm.nih.gov/pubmed/37475869 http://dx.doi.org/10.3389/fimmu.2023.1177624 |