B cell abnormalities and autoantibody production in patients with partial RAG deficiency

Mutations in the recombination activating gene 1 (RAG1) and RAG2 in humans are associated with a broad spectrum of clinical phenotypes, from severe combined immunodeficiency to immune dysregulation. Partial (hypomorphic) RAG deficiency (pRD) in particular, frequently leads to hyperinflammation and a...

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Detalles Bibliográficos
Autores principales: Min, Qing, Csomos, Krisztian, Li, Yaxuan, Dong, Lulu, Hu, Ziying, Meng, Xin, Yu, Meiping, Walter, Jolan E., Wang, Ji-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354446/
https://www.ncbi.nlm.nih.gov/pubmed/37475856
http://dx.doi.org/10.3389/fimmu.2023.1155380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354446/
https://www.ncbi.nlm.nih.gov/pubmed/37475856
http://dx.doi.org/10.3389/fimmu.2023.1155380

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