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Sensitivity analysis of biochemical systems using bond graphs

The sensitivity of systems biology models to parameter variation can give insights into which parameters are most important for physiological function, and also direct efforts to estimate parameters. However, in general, kinetic models of biochemical systems do not remain thermodynamically consisten...

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Detalles Bibliográficos
Autores principales: Gawthrop, Peter J., Pan, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354489/
https://www.ncbi.nlm.nih.gov/pubmed/37464805
http://dx.doi.org/10.1098/rsif.2023.0192