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Sensitivity analysis of biochemical systems using bond graphs
The sensitivity of systems biology models to parameter variation can give insights into which parameters are most important for physiological function, and also direct efforts to estimate parameters. However, in general, kinetic models of biochemical systems do not remain thermodynamically consisten...
Autores principales: | Gawthrop, Peter J., Pan, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354489/ https://www.ncbi.nlm.nih.gov/pubmed/37464805 http://dx.doi.org/10.1098/rsif.2023.0192 |
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