Cargando…

The link between relative stability constant of DNA- and BSA-chromenopyrimidine complexes and cytotoxicity towards human breast cancer cells (MCF-7)

In this study, we synthesized and characterized ten chromenopyrimidine derivatives using analytical and spectroscopic methods. Studies on DNA and albumin binding affinity, as well as cytotoxicity tests on human breast cancer (MCF-7) cells, of the chromenopyrimidines, were conducted. The natural loga...

Descripción completa

Detalles Bibliográficos
Autores principales: Zamisa, Sizwe J., Adeleke, Adesola A., Devnarain, Nikita, Rhman, Mahasin Abdel, Owira, Peter M. O., Omondi, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354499/
https://www.ncbi.nlm.nih.gov/pubmed/37475760
http://dx.doi.org/10.1039/d3ra01741a