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The link between relative stability constant of DNA- and BSA-chromenopyrimidine complexes and cytotoxicity towards human breast cancer cells (MCF-7)
In this study, we synthesized and characterized ten chromenopyrimidine derivatives using analytical and spectroscopic methods. Studies on DNA and albumin binding affinity, as well as cytotoxicity tests on human breast cancer (MCF-7) cells, of the chromenopyrimidines, were conducted. The natural loga...
Autores principales: | Zamisa, Sizwe J., Adeleke, Adesola A., Devnarain, Nikita, Rhman, Mahasin Abdel, Owira, Peter M. O., Omondi, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354499/ https://www.ncbi.nlm.nih.gov/pubmed/37475760 http://dx.doi.org/10.1039/d3ra01741a |
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