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Yes-associated protein-1 overexpression in ocular surface squamous neoplasia; a potential diagnostic marker and therapeutic target

Yes-associated protein-1 (YAP-1) is a Hippo system transcription factor, which serves as an oncogene in squamous cell carcinoma, and several solid tumors when the Hippo pathway is dysregulated. Yet, the activity of YAP-1 in ocular surface squamous neoplasia (OSSN) has not been determined. Here, we i...

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Detalles Bibliográficos
Autores principales: Julius, Peter, Siyumbwa, Stepfanie N., Maate, Fred, Moonga, Phyllis, Kang, Guobin, Kaile, Trevor, West, John T., Wood, Charles, Angeletti, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354641/
https://www.ncbi.nlm.nih.gov/pubmed/37476371
http://dx.doi.org/10.3389/fonc.2023.1213426