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Soluble CD80 oral delivery by recombinant Lactococcus suppresses tumor growth by enhancing antitumor immunity

CD80 is an important co‐stimulatory molecule that participates in the immune response. Soluble CD80 can induce T cell activation and overcome PDL1‐mediated immune suppression. In this study, we aimed to construct recombinant Lactococcus lactis for oral delivery of the soluble CD80 (hsCD80) protein o...

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Detalles Bibliográficos
Autores principales: Lin, Ziqing, Tang, Yanqing, Chen, Zerong, Li, Simin, Xu, Xueyan, Hou, Xufeng, Chen, Zhenhui, Wen, Junjie, Zeng, Weisen, Meng, Xiaojing, Fan, Hongying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354755/
https://www.ncbi.nlm.nih.gov/pubmed/37476068
http://dx.doi.org/10.1002/btm2.10533