Theranostic mesoporous platinum nanoplatform delivers halofuginone to remodel extracellular matrix of breast cancer without systematic toxicity

The enriched collagens in the extracellular matrix (ECM) of breast cancer substantially impede drug delivery. Halofuginone (HF), a potent antifibrotic agent, was effective to deplete the collagens and remodel the ECM by inhibiting the TGFβ pathway. However, the application of HF was hindered by its...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Xu, Ziqing, Li, Yang, Hu, Yongzhi, Tang, Jiajia, Xu, Jiaqi, Luo, Yafei, Wu, Feiyun, Sun, Xiaolian, Tang, Yuxia, Wang, Shouju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354758/
https://www.ncbi.nlm.nih.gov/pubmed/37476071
http://dx.doi.org/10.1002/btm2.10427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354758/
https://www.ncbi.nlm.nih.gov/pubmed/37476071
http://dx.doi.org/10.1002/btm2.10427

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