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Association of C>U RNA Editing with Human Disease Variants

RNA-editing is an important post-transcriptional RNA sequence modification performed by two catalytic enzymes, “ADAR”(A>I) and “APOBEC”(C>U). Although APOBEC-mediated C>U editing has been associated with a number of human cancers, the extent of C>U editing in human disease remains unclea...

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Detalles Bibliográficos
Autores principales: MANDLOI, Sapan, FALLS, Zackary, DENG, Rong, SAMUDRALA, Ram, ELKIN, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354784/
https://www.ncbi.nlm.nih.gov/pubmed/32570581
http://dx.doi.org/10.3233/SHTI200364