Predicting the Mitochondrial Toxicity of Small Molecules: Insights from Mechanistic Assays and Cell Painting Data

[Image: see text] Mitochondrial toxicity is a significant concern in the drug discovery process, as compounds that disrupt the function of these organelles can lead to serious side effects, including liver injury and cardiotoxicity. Different in vitro assays exist to detect mitochondrial toxicity at...

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Detalles Bibliográficos
Autores principales: Garcia de Lomana, Marina, Marin Zapata, Paula Andrea, Montanari, Floriane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354797/
https://www.ncbi.nlm.nih.gov/pubmed/37409673
http://dx.doi.org/10.1021/acs.chemrestox.3c00086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354797/
https://www.ncbi.nlm.nih.gov/pubmed/37409673
http://dx.doi.org/10.1021/acs.chemrestox.3c00086

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