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Asymmetric Voltage Attenuation in Dendrites Can Enable Hierarchical Heterosynaptic Plasticity

Long-term synaptic plasticity is mediated via cytosolic calcium concentrations ([Ca(2+)]). Using a synaptic model that implements calcium-based long-term plasticity via two sources of Ca(2+) — NMDA receptors and voltage-gated calcium channels (VGCCs) — we show in dendritic cable simulations that the...

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Detalles Bibliográficos
Autores principales: Moldwin, Toviah, Kalmenson, Menachem, Segev, Idan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354808/
https://www.ncbi.nlm.nih.gov/pubmed/37414554
http://dx.doi.org/10.1523/ENEURO.0014-23.2023